Cart
sales@molnova.com
FC131 TFA
CAS No. ——
FC131 TFA( —— )
Catalog No. M22521 CAS No. ——
FC131 TFA is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 828 | In Stock |
|
| 10MG | 1382 | In Stock |
|
| 50MG | Get Quote | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameFC131 TFA
-
NoteResearch use only, not for human use.
-
Brief DescriptionFC131 TFA is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv activity.
-
DescriptionFC131 TFA is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv activity.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAutophagy
-
TargetCXCR
-
RecptorCXCR4|HIV
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number——
-
Formula Weight843.85
-
Molecular FormulaC38H48F3N11O8
-
Purity>98% (HPLC)
-
SolubilityDMSO:250 mg/mL (296.26 mM; Need ultrasonic)
-
SMILESFC(F)(F)C(=O)O.N=C(N)NCCC[C@@H]4NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](Cc2cc3ccccc3cc2)NC4=O)CCCNC(=N)N
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Tamamura H, et al. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. J Med Chem. 2005 Jan 27;48(2):380-91.
molnova catalog
related products
-
CHIR98014
CHIR 98014 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
-
Syringaresinol-di-O-...
1. Syringaresinol-di-O-glucoside protects the animals from the stress-induced decreases in sex behaviours and in rectal temperature, the stress-induced failure of retrieval of memory, and the stress-induced enlargement of adrenal gland.
-
CXCL-CXCR1/2-IN-1
CXCL-CXCR1/2-IN-1 is an orally active and potent inhibitor of the ELR+CXCL-CXCR1/2 pathway with anticancer and anti-angiogenic activity and can be used to study cardiovascular disease and cancer.
